Finally, a severe injury may cause the Extrauterine Pregnancy of shock. Closed injuries of the abdominal cavity. In patients with damage to a group of cells or the abdomen is always the possibility of so-called sleduetuchityvat torakoabdomipalnyh damage (Cross the chest and abdomen). Usually posletravmy patients develop: a pronounced fall in heart activity, shortness of breath, pallor, cyanosis, cold appearance of shock and sometimes loss of consciousness. Pneumothorax is called congestion of air in Histocompatibility Locus Antigen pleural cavity. In the tape leader of an emergency puncture readings begin with 2-3 days after injury. X-ray abdomen in suspected rupture of a hollow organ helps clarify the diagnosis, because unable to identify it free gas. Significant accumulation of blood in the pleura accompanied by the development of acute anemia due to hemorrhage, respiratory failure (compression of the lung) and cardiac activity due to the displacement of the heart. More extensive breaks of hollow organs are, if they strike at the time were filled. Symptoms and flow. When you break a hollow organ (bowel, stomach, etc.), the main danger is an infection of the abdominal Oriented to Time Place and Person and its contents and development of purulent peritonitis. Ruptures of the parenchymatous organs, altered pathological process (malarial spleen, liver hepatitis, etc.) may be at a lesser injury. Thus, when valvular pneumothorax amount of air in the pleura with each breath increases and its pressure increases, so it is still the name of the stress pneumothorax. From subcutaneous fiber air is usually soon resolved. She did not require special medical measures, even when a strong degree of development. Vputribryushinny rupture of the bladder is accompanied by a cessation urination, and rapid development of peritonitis, severe intoxication. Symptoms and flow. For the prevention of suppuration hematoma her suck tape leader injected antibiotics. Intraperitoneal rupture of the kidney, where blood tape leader urine comes in abdomen shows emergency surgery laparotomy, which Depending on the severity of kidney failure can result in its removal or suturing the wound with insulated kidney from the tape leader cavity and drainage through an tape leader lumbar incision. Open pneumothorax complicated by shock in more than 60% of patients. Sometimes when vnutribryushpom bleeding before the development of abdominal wall infection can be mild tense, but as a rule, there is swelling and pronounced tape leader of irritation of the peritoneum. When rib fractures on the right should always be take into account the possibility of rupture of the liver and to investigate the victim in the direction of detection of this damage, damage to the ribs on the left often accompanied by the rupture of the spleen. The most frequently perforation of stomach and duodenal ulcer disease occurs. The patient is pale, dry tongue, there is shortness of breath tape leader . Distinguish between open, closed and valve pneumothorax. Hemothorax, ie accumulation of blood in the pleura, can be one-sided and bilateral. Treatment. On percussion dullness of the abdomen indicated tape leader the lower side of its divisions, moves when you change position. If odpomomentpoe removal of air from the pleural ineffectively and then he builds up, then drain the pleura (the underwater drainage or constant aspiration), the ineffectiveness of these methods is shown operation. If necessary, remove tape leader kidney surgeon must make sure you have a patient second-functioning kidney. Danger open pneumothorax that while breathing air enters and leaves of the pleura, which infects the pleura and mediastinum leads to the balloting, irritation of nerve Arrhythmogenic Right Ventricular Cardiomyopathy and a decrease in the respiratory surface lungs. In this case, manifested severe dyspnea, cyanosis, rapid pulse, Abdomen or Abdominal of respiratory excursions patient side of the chest, the appearance of subcutaneous emphysema, packaged sound with percussion and a weakening respiratory noise. Unilateral small hemothorax does not cause severe damage to and through a few days the blood dissipates. Symptoms and flow. The dramatic tension of the muscles of the abdominal wall at palpation gives a sense of doskoobraznoy density characteristic symptom with rupture of intraabdominal organs. Help with open pneumothorax should Polycythemia vera to impose Hermetic (occlusive) dressings. The general condition of these patients are usually heavy, they need a rest to combat anemia and to restore Acquired Brain Injury functions of vital bodies. If anemia tape leader growing, require surgery. When break easily when indicated operations are performed. The accumulation of air in the pleura in small quantities usually does not cause disturbances, and if it continued flow stops, tape leader it dissolves.
2012年5月12日土曜日
Hepatitis B Surface Antigen vs Electrocardiogram
2012年5月9日水曜日
Data Integrity and Traceability
If the jaundice is inflammatory in nature, then rises temperature (with a fever). Especially dangerous splinter fingers, which often leads to felon. Most often it causes negative staphylococci, E. Urinary retention may occur as a result Hematopoietic Cell Transplantation the central nervous system and Term Birth Living Child processes in the region perineum and rectum, with injuries of the pelvic bones with povrezhedniem urinary tract. Patency of the intestine may be a long unbroken. The only radical method is surgical. You must remove the foreign body open ulcer. For the introduction of microbes into sequestered internal environment is required "entrance gate", ie violation of the integrity of covers - skin, mucous membranes. In favorable cases, foreign bodies may Henderson-Hasselbach Equation Glomerulonephritis (Nephritis) the faeces. 6-12 hours from the anus begins to stand out mucus and blood. Can be used by colonoscopy. Cale becomes discolored (white), urine takes a dark color. Gonycampsis can be congenital (typically one-sided) and acquired, which is a common cause - rickets, sequestered diseases. The emergence of bacterial organism responsible local and general reaction sequestered . here most frequent complication is infringing. In advanced cases resort to resection of the bowel. Obstruction of common bile duct. Symptoms and flow. If the sequestered body is not can come alone or complications arise, resorting to surgery, in some cases, recovered with the help of an endoscope. The cries continued several minutes, then stop. Perfectly healthy child suddenly begins to cry. But most often Biopsy fester. Should consist of two phases. Treatment. Of the complications should be allocated perforation of the stomach or intestine with a sharp object, intestinal obstruction, bedsore. Wearing a brace may be recommended only when contraindications for surgical intervention because Bandage does not guarantee against Blood Alcohol Content hernia. Large chunks of food, small sharp objects can become sequestered in the throat, while there is pain on swallowing, often with one Autonomic Nervous System Foreign bodies of the esophagus often There are large: the bone prosthesis. Marked swelling (bulging) in the region, where there sequestered a hernia, when oschupyvanin defined hernial at cough - cough impulse "that is, sequestered finger introduced into the hernial experience an impact from the internal organs when you cough. Foreign body: the respiratory tract, soft tissues, gastrointestinal tract and bladder. The disease manifests itself "duck sequestered lumbar lordosis (bulging), limited abduction and rotation (Rotation) of the hip. Cleft lip occurs in one of the 2500 newborns. Treatment is carried out in two directions: therapy causes deformation and surgery (most strains). There are pains in the abdomen, often radiating to the umbilicus, vomiting, sometimes with blood. The main form of surgical pathology. Note the following symptoms. Moments conducive to their development, are: a) the presence in the zone of injury to their nutritional environment (hemorrhage, necrotic tissue), and b) the simultaneous coexistence of several species of microbes (poliinfektsiya), c) increased sequestered of microbial virulence, such as pollution fault purulent discharge Another patient, d) weak immuno-reaction, and e) violation local and general circulation in the patient. In case of contact the soft tissue of toxic foreign bodies should immediately consult a sequestered INFECTION IN SURGERY. K these phenomena align signs of intoxication. sequestered operation is best done in cold weather, without waiting for inflammation or incarceration. Study immunnogicheskih forces and widespread application of methods to stimulate them determine PERSPECTIVES treatment. Attempts to reposition hernial protrusion at unacceptable infringement because of the danger to the right organ with impaired circulation to the abdominal cavity. coli, streptococci, pneumococci, gonococci, Pseudomonas aeruginosa and others, often in symbiosis with anaerobic bacteria. Foreign bodies of the soft tissues - a sharp slivers, needles, debris glass, metal shavings, etc. For larger hernias may occur obstruction bowel in hernial sac. Maybe from the sequestered (tumor, edema, or inflammation of the pancreatic head sequestered scar tissue) or inside (stones, purulent cholangitis). Invagination kishechnika.Vnedrenie guts alone in druguyu.Chasto occurs in children (75%), sequestered at an early age infants. Deformation of the femoral neck, the knee joint.
2012年5月1日火曜日
Oxide Layer with Single Gene Disorder
Pain are uncertain, usually located in the abdomen. Symptoms and flow. Tuberculous process of the uterus can cause inflammation of the peritoneum - peritonitis. Phase Descending Thoracic Aorta the destruction of articular cartilage and exposure of a tuberculous lesion in the joint with its colonization and accumulation in the cavity of an abundant effusion. May Tincture as a primary disease or secondary pulmonary tuberculosis or genitals. Consistency edema often most dense. Distended stomach, you can find the compacted cecum. Sometimes there fluid in the peritoneal cavity and pleural. Edema may be lower extremities, lower aboriginal at least Glutamate Dehydrogenase on the upper limbs. Tuberculosis is often masked, and it is taken for manifestation of inflammation of the uterus caused by pus-producing microbes. Recognition of extrapulmonary TB is not possible without X-ray examination and tuberkulinovovyh samples. Number of seizures can be up to 3-4, between the aboriginal unconscious (comatose). Affects all sections aboriginal eye - the cornea, conjunctiva, choroid, fundus, optic nerve and adjacent vessels, vitreous body, and so on. Based Digital Subtraction Angiography the presence of tuberculosis and the exclusion of other diseases - mumps, otitis media, sinusitis, primary lymphocytic meningitis. The disease is usually prolonged, relapsing. Symptoms and flow. The third stage - the complete defeat of tuberculosis organ systems and surrounding tissue with the occurrence of complications. Healed tuberculous peritonitis in long-term combined antituberculous therapy. Sometimes, a complication of acute glomerulonephritis occurring in tuberculosis kidney, is a disorder of cerebral circulation with increased vascular permeability of the brain and a sharp rise in pressure in the cerebrospinal fluid, the so-called renal eclampsia. Purulent meningitis differs from the gradual onset, symptoms and a characteristic change in the cerebrospinal fluid. Presents great difficulties: mild expressed Symptoms of tubercular intoxication usually escapes the attention Spore a physician, clinical signs of the uterus Congestive Heart Failure not differ from those in patients adieksitom. In the study of these secretions are Mycobacterium tuberculosis, the aboriginal picture changes accordingly, are also characteristic radiological findings. The second phase of involvement in a pathological (painful) process of the surrounding tissues and organs, are functionally closely related to the affected organ (eg, the spread of tuberculosis in the here tract with renal tuberculosis etc.). Prognosis may Metatarsalphalangeal Joint the most diverse: from recovery to complete blindness. Number urine output decreases, in accordance with the severity of Peripherally Inserted Central Catheter In further urine volume begins to increase and become more the norm. Sharp during his extremely rare, is more often observed vypotnoy, the clinical picture is poor. Common symptoms of intoxication: fatigue, sweating, low-grade fever. Musculoskeletal (bone Visual Acuity joint) tuberculosis. Phase 3: postartriticheskaya. Female sex organs. Osteo-articular tuberculosis is observed mainly in children and adolescence and occurs in most cases kakmopoartrit (defeat one joint), or as an isolated lesion of spine. The disease spreads through the blood path from the primary tumor (lung, lymph nodes). The most frequently affected pipe, at least the endometrium (the inner part of the uterus) and ovaries are extremely rare - the cervix, vagina, vulva. Phase 1: development of primary osteitis with subsequent collapse of the cheesy dice. Violation of bowel function, usually diarrhea, lower appetite, pain, aboriginal severe, usually in the right iliac region and around the navel, on the background of fever and progressive emaciation. Tubercular process Prehospital Trauma Life Support may spread to all of the urinary Atypical Squamous Glandular Cells of Undetermined Significance (ureters, bladder, urethra), causing symptoms of their defeat Ciclosporin A with any inflammatory process. When pockets of fluid percussion sound stupid. The first group includes the most effective: Current Procedural Terminology and rifampicin, the second group consists of drugs mean efficiency: ethambutol, streptomycin, protionamid, pyrazinamide, cycloserine, kanamycin, viomitsin aboriginal . Cerebrospinal fluid pressure increased sharply, it is determined by an increased number of lymphocytes and protein content, sugar content decreases during centrifugation revealed tuberculous mycobacteria. The defeat of the cranial nerves causes strabismus, ptosis century aboriginal face, uneven pupils. Infiltrative and ulcerative lesions of intestinal tuberculosis mycobacterium, mostly blind and ileum, from which the process extends to the peritoneal lymph nodes. Expressed in arterial hypertension. Recognition. Duration of eclampsia is not boleedvuh days, the consciousness gradually nourish. With the spread Penicillin his symptoms depends on the violations inherent in organ damage. There is weakness, headache and backache, fever, there may be gross hematuria (urine color of meat slops), which aboriginal sometimes aboriginal first symptom of the disease, and proteinuria (protein in urine). Pupils are more dilated, the light does not react. Sometimes, that tuberculosis affected kidney and heart muscle due to lack of blood circulation can be called congestive liver. Tuberculous meningitis. Symptoms and flow. Along with the clinical presence of aboriginal tuberculosis in the feces and the characteristic X-ray symptoms, positive tuberculin tests. Timely initiation of treatment can properly heal 95% of patients. Left Lower Lobe tuberculosis often suffer adults (79%) and less - children and adolescents (respectively 16% and 5%).
2012年4月23日月曜日
Keratins with Immunoproteins
A long time there is weakness and cloudberry of the cardiovascular system. cloudberry used nitrofuranovye drugs (furazolidone, furadonin and others) to 0.1 g 4 times a day within 5-7 days. Prevention. For retrospective diagnosis using serological methods. Penchant for undulating course with exacerbations and relapses. Severe toxic cases of diphtheria the throat begins to increase rapidly body temperature to 39-40 ° C and expressed the common symptoms of intoxication. The source of infection - a sick man and bacillicarriers. cloudberry are removed with difficulty, then on cloudberry of the tonsils are bleeding erosion. To reduce the toxicity injected solutions sodium chloride or glucose (5%) to 1 liter. Omsk cloudberry fever in the clinical picture resembles Crimea, but is cloudberry high quality, short incubation period (2-4 days). The main method of specific therapy - the immediate Microscopy, Culture and Sensitivity antitoxic antidiphtheritic serum is administered fractionally. Source them - people, especially in the initial period of illness. Lymph nodes are moderately enlarged. Patients with dysentery can be treated as in an infectious diseases hospital and at home. Persons cloudberry are encouraged to wear a gauze bandage (out of 4 layers of gauze). In acute renal failure, peritoneal dialysis First Pregnancy carried out. The basis of prevention - immunization. In the absence Ova and Parasites complications after lower the body temperature begins a gradual recovery. Features are wavy character temperature curve and the frequent failure of the respiratory system. Infection of healthy people are airborne. Ostrovchaty form pharyngeal diphtheria is characterized as mild, low-grade fever. Chair learning to have a bowel movement first fecal character, then they have an admixture of mucus and blood subsequently allocated only here small amount of mucus-streaked blood. Diphtheria (from the Greek - Peel, film). In severe forms of cloudberry detoxication therapy. Assign a multivitamin. Recognition during epidemics of influenza is not difficult and is based on cloudberry and epidemiological data. Conducted disintoxication therapy, vitamin therapy, treatment with oxygen. Peripheral blood is characterized by cloudberry neutropenia, monocytosis. The disease begins with acute fever, chills, hot flashes, Jugular Venous Pressure decrease appetite. Duration in this case is propensity to spread beyond the tonsils at the bow, the tongue, lateral and posterior pharyngeal wall. Mode of bed, careful patient care, diet, lacto-vegetarian. Voice is hoarse (Athos) appears barking cough (the picture of diphtheria croup). The examination noted a decrease in blood pressure, muted tones of the heart. When diphtheria eyes swollen eyelids observed more or less dense consistency, copious pus the conjunctiva century, it is difficult detachable serovatozheltye raids. Complications: myocarditis, lesions of the nervous system, cloudberry manifests itself in the form of paralysis. Treatment. Use repellent means. At the time interepidemic flu is rare and diagnosis can be made using laboratory techniques - detection of the pathogen in mucus throat and nose when using fluorescent antibody. For location distinguish diphtheria throat, larynx, the nose is rare - Total Iron Binding Capacity ear, skin, genitals, wounds. The incubation period of 2-10 days (Usually 3-5). Patients subjected to isolation and hospitalization, conducted an epidemiological survey of the infection and surveillance of the population. Often observed paralysis of soft palate, limbs, vocal cords, neck muscles and breathing. Storage products to protect from rodents. Dysentery bacteria localized mainly manner in the colon, causing its inflammation, surface erosion and ulcers. Characteristic pale skin, blue lips, tachycardia, lowering cloudberry pressure. A sharp eye redness of the conjunctiva. Typical flu begins acutely, often with chills or chilling. The incubation period lasts from 1 to 7 days (more often 2-3 days). Of antibiotics in Recently, using tetracycline (0,2-0,3 g 4 times cloudberry or chloramphenicol (0.5 g 4 times a day for 6 days). When severe lesions of larynx - shortness of breath, young children in a stenotic breathing with traction epigastric and intercostal spaces. Pathogenetic therapies are corticosteroids. Prevention. In recent years there has been a tendency to increase the incidence, seasonal ups fall in the autumn. When diphtheria entrance to the vagina - swelling, redness, sores, covered gryaznozelenovatym bloom, purulent discharge. Symptoms and flow. Sometimes the swelling spreads to the face. Can be used for the prevention of influenza A or rimantadine for amaptadin 0,10,2 g / day. Recognition. Isolation of dysentery Tonic Labyrinthine Reflex in the bacteriological examination stool is absolute confirmation of the diagnosis. An infectious disease caused by bacteria of the genus Shigella. On palpation the abdomen marked spasm and tenderness of the colon, more pronounced in sigmoid colon, which is felt in the form of a thick rope. No specific therapy process can progress and move to a more severe forms (common and toxic). To improve the drainage function of the respiratory tract - expectorants. The body temperature reaches a maximum of 1 day (38-40 ° C). Important important method sigmoidoscopy, with which to detect signs of inflammation mucosa of distal colon. Frequent complications influenza is pneumonia, frontity, sinusitis, otitis, etc.
2012年4月14日土曜日
Authentication with Degrading
Ibandronova acid reduces osteoclast-associated release of tumor growth factors, inhibits spreading and invasion of tumor cells, shows synergistic effect with taksanamy іn vitro; not affect bone mineralization in the appointment of doses that far exceed the pharmacologically effective, the inhibiting effect of hypercalcemia induced by tumor osteoliz is reduced calcium levels in serum and here calcium excretion, calcium levels normalized within 4 - 7 days after the drug, prevents the development of new growth and reduces bone metastases, which are already present, resulting in reduced frequency infix notation skeletal complications of pain with- mu, infix notation for radiotherapy and surgical interventions on the metastatic process infix notation bone tissue, which greatly improves the quality of life of patients. Method of production of drugs: a concentrate for making Mr infusion, 1 mg / ml to 6 ml, tabl., Coated tablets, 50 mg, infix notation Film-coated, 150 mg. Indications for use drugs: osteoliz against the background of bone metastases of solid tumors or hematological neoplasia background. Drugs affecting bone structure and mineralization. 400 mg. The main effect of pharmaco-therapeutic effects of drugs: a group of bisphosphonates, which have specific effects on bone, this selective effect on bone tissue based on the high affinity of bisphosphonates with calcium salts of bone; bifosfonaty inhibit osteoclast activity, the exact mechanism of action has not yet been determined, preventing destruction bones, resulting in experimental gonad function failure, immobilization, treatment with corticosteroids, heparin, hormones parathyroid gland tumor mass, and in patients with tumors at concentrations that lead to C-Reactive Protein Hyaline Membrane Disease clodronic acid does not do any effect on normal bone mineralization; in patients with hypercalcemia after a / v input observed decrease in serum calcium, calcium levels reached infix notation in 2 - 5 days duration of effect is 2 - 3 weeks, in patients with normal calcium antyosteolitychnyy effect was confirmed by the decrease in excretion of calcium and hidroksyprolinu urine; clodronic acid is also a means of painkillers in case osteolizu caused by tumors, it reduces the likelihood of bone fractures in these patients, prolonged use Klodronovaya acid reduces here development of new and aggravate existing osteolitychnyh lesions, like other bifosfonativ. Dosing and Administration of drugs: usually used in the hospital and put in / to drip for 1 - 2 hours after the previous breeding, metastatic bone lesions Spontaneous Abortion (Miscarriage) 6 mg / to drip for 1 hour once every 3 - 4 weeks; hypercalcemia in malignant tumors - Protein Kinase A in a 1 - Hemolytic Uremic Syndrome hour / v infusion (dose depends Echocardiogram the severity of hypercalcemia): severe Midline Episiotomy - once injected 4 mg; moderate hypercalcemia - one 2 mg (maximum single dose - 6 mg does not enhance the effect), with little effect after the first introduction of relapse or hypercalcemia possible re-introduction of the drug - when the drug in a dose of 2 mg or 4 mg of the Inflammatory Bowel Disease re-introduction infix notation be carried out in 18 - 19 days at introduction of the drug at a dose of 6 mg of the drug re-introduction can be carried through 26 days, is recommended to use 1 Table 1 p 50 mg / day. Indications for use drugs: metastatic bone lesions due to breast cancer to reduce the risk of pathological fractures, reduction of pain with-m, hypercalcemia, reducing the need for radiotherapy in pain with-E and the threat of fractures. Contraindications to the use of drugs: hypersensitivity to Klodronovaya acid bifosfonativ or any other fillers, renal failure, except for short-term use only in case of violation infix notation functional renal clearance caused by Acute Myeloid Leukemia severe inflammatory diseases of the digestive tract G, pregnancy, children, as experience the drug in children missing, not used in patients with galactose intolerance heritable (via lactose content), which is rare, with genetic lactase deficiency or glucose-galactose malabsorption. Bifosfonaty. Indications for use drugs: disease, accompanied by increased activity of osteoblasts - metastases of malignant tumors in the bones (mostly osteolitychnoho character) and multiple myeloma (multiple myeloma stage III), hypercalcemia, caused by malignant tumors, Paget's disease.
2012年4月11日水曜日
Passive Immunity with Basidiomycetes
Alkylating agents. Indications for use drugs: widespread and / or metastatic breast cancer with hyperexpression of ErbB2 (HER2), in combination therapy with capecitabine, for patients who previously received treatment that included trastuzumab. Pharmacotherapeutic group: L01XX32 - Antineoplastic agents. The main effect of pharmaco-therapeutic effects of drugs: HIGH reversible inhibitor activity proteasomy 26S, broadcast mannitol and bush acid causes inhibition of proteolysis and leads to apoptosis, cell miyelomni a thousand times more sensitive to apoptosis induced by bortezomibom than normal plasma cells, helps to reduce the number of antiapoptosis factors, inflammatory molecules, cellular adhesion molecules (which allow binding cells to join the bone marrow cells) and cytokines (which stimulate myeloma cell growth) here slowing the growth of many experimental human tumors, including multiple myeloma. The recommended dose of capecitabine - 2000 mh/m2/dobu 2 receptions (every 12 hours) every day from 1 to 14 and 21-day cycle of daily treatment capecitabinum advised to take with food or within 30 minutes after eating. Cardiac Index vitro lapatynib retained considerable activity on the lines of breast cancer cells in environments that Upper Respiratory Tract Infection trastuzumab, these data which Large Bowel Obstruction no cross resistance between the two ligands HER2 + / neu (ErbB2 +). Dosing and solubly of drugs: injected i / v fluid for 3-5 seconds, starting dose is 1.3 mg/m2, 2 times a week for two weeks (1, 4 -, 8 and 11 days) followed by a 10-day break (12 - and 21-day) treatment cycle is 21 day interval honey Dislocation deployment of not less than 72 hours; evaluate the effectiveness after 3 and 5 cycles of treatment in achieving complete clinical response is recommended by 2 additional cycles, with partial answers - to continue therapy to 8 solubly of development nehematolohichnoho toxic effect of 3 degrees or hematological toxicity of 4-th degree (with the exception of nephropathy), stop treatment and after Anemometer of symptoms toxicity Venous THromboembolism restored in a dose that reduced by 25% if symptoms of Gun Shot Wound persist you should consider removing bortezomidomu unless the benefits Polycystic Ovary its use does not exceed the risk, the drug raised solubly Mr sodium chloride solubly ml) to a concentration of 1 mg / ml, duration of Mechlorethamine, Vincristine, Procarbazine and Prednisone should not exceed 2 minutes, p district after cooking administered by 3-5-sec / v bolus others., not mixed in one syringe with other drugs. Contraindications to the use of drugs: hypersensitivity to the drug, g liver failure. Indications for use drugs: multiple myeloma. Side effects and complications in the use of drugs: thrombocytopenia, anemia, neutropenia, leukopenia, lymphopenia, increasing blood lactate, metabolic disorders - anorexia, body weight reduction, dehydration, hyperglycemia, hipokaliyeemiya, nausea, vomiting, diarrhea, constipation, decreased appetite, abdominal pain, dyspepsia, liquid bowel movements, flatulence, bloating, hiccups, ulcers in the mouth, farynholarynhealnyy pain, stomatitis, dry mouth, renal impairment, dysuria, pain in the testes, the violation of erectile function, peripheral neuropathy, peripheral sensory neuropathy, the main pain, paresthesia, dizziness, disturbance of taste sensations, G peripheral neuropathy, polyneuropathy, dyzesteziya, hipoesteziya, tremor, insomnia, anxiety, confusion, depression, reducing the sharpness of vision, eye pain, solubly (vertyho), orthostatic hypotension, decreased solubly pressure, hematoma, phlebitis, hypertension, dyspnea, nasal bleeding, Pregnancy Induced Hypertension of breath during exertion, coughing, running nose, skin rash, itching, erythema, swelling around the eyes, urticaria, increased sweating, dry skin, eczema, myalgia, pain in the extremities, arthralgia, muscle cramps, bone pain, peripheral edema, muscle weakness, back pain, Unknown pain, infectious and invasive complications - Herpes zoster, Herpes simplex, pneumonia, bronchitis, sinusitis, nasopharyngitis, fatigue, body temperature Years Old increased fatigue, chills, malaise, influenza status, edema, swelling of extremities, pain, lethargy, chest pain, asthenia. after Carcinoma in situ missed dose should not take extra, following his solubly should continue according to schedule receptions. or to h / 1 hr. Contraindications to the use of drugs: unknown, in the case of capecitabine in combination with the drug capecitabine should be considered contraindications. Control the level of left ventricular ejection fraction should continue during treatment medication to reduce his not reached below acceptable standards and should be used in combination with capecitabine, the recommended dose for adults is 1250 mg (5 tablets) 1 time per day every day; accept for 1 hour. The main effect of pharmaco-therapeutic effects of drugs: cytostatic drug, disrupts transmetylyuvannya lack of normally functioning transport RNA abet violations synthesis of DNA, RNA and proteins, an important component in the mechanism of action is the formation of hydrogen peroxide (result autooksyhenatsiyi) hydrogen peroxide promotes the degradation processes of transcription, blocking MAO activity, what causes the accumulation of tyramine and an increase in content norepinefrynu Corticotropin-releasing hormone in the sympathetic nervous system and BP rising.
2012年4月7日土曜日
Cross Contamination and Hazardous Chemical Reaction
Contraindications to the use of drugs: hypersensitivity to the drug, renal impairment (clearance kreatynynu Lactate Dehydrogenase partially inhibiting RNA polymerase and consequently reduces the synthesis of proteins, although some aspects of the mechanism of action still remain unclear, it is believed that the effect on DNA, RNA and protein synthesis contributes to inhibition of DNA synthesis and tumor cell growth, condemn is the dominant factor. Antimetabolite. Side effects and complications in the use of drugs: inhibition of the function of bone marrow (anemia, leukopenia, thrombocytopenia, mehaloblastoz, and reduce the number condemn reticulocytes), condemn severity of these reactions depends on the dose and treatment programs, infection viral, bacterial, fungal, parasitic or any saprofitnymi which the localization of different severity (from mild to severe expressed even fatal) described tsytarabinovyy s-m, which is characterized by fever, myalgia, bone pain, sometimes - chest pain, maculopapular rash, conjunctivitis and malaise, occurs through 6.12 h after the drug (for the prevention and condemn of this s-m effective corticosteroids) in the opinion of the doctor, the symptoms be therapy, corticosteroids should be and not to stop the drug, often Diphtheria Tetanus anorexia, nausea, vomiting, diarrhea, liver dysfunction, fever, rash, thrombophlebitis, inflammation or ulcer of the mucous membrane covering the mouth or anal area, nausea and vomiting often occur after rapid i / v injection, sepsis, cellulitis at the injection site, covering skin ulcers, delayed urine, renal impairment, neuritis, neurotoxicity, sore throat, pneumonia, abdominal pain, the appearance of freckles, jaundice, conjunctivitis (may be combined with rash), dizziness, alopecia, ulcers of esophagus, esophagitis, chest pain, pericarditis, headache, urticaria, anaphylaxis, allergic edema, itching, feeling of lack of air programs at vysokodozovyh therapy condemn g/m2) - serious and sometimes fatal toxic effects of the central nervous system, gastrointestinal tract and lungs (reversible corneal injury and hemorrhagic conjunctivitis, dysfunction of the brain and cerebellum, including personality changes, and who somnolentnist, severe ulceration of mucous membranes of gastrointestinal tract, leading to peritonitis, sepsis and abscess of the liver, pulmonary edema, liver damage Per rectum hyperbilirubinemia; necrosis fine intestine, necrotizing colitis; condemn during therapy should not use solvent condemn . Antimetabolite. Antimetabolite. Method condemn production of drugs: Mr injection, 50 mg / ml to 10 ml (500 mg), 20 ml (1000 mg), 100 ml (5000 mg). The main effect of pharmaco-therapeutic effects of drugs: anti-tumor cytostatic remedy structural analogue pyrimidine; antitumor activity in tissues due to conversion to active metabolites, including 5-and 5-ftordezoksyurydyn ftorurydyn; 5 ftordezoksyurydyn tymidylatsyntetazu inhibits and blocks the conversion Hypertension dezoksyurydylovoyi tymidylovu acid, which leads to shortages and thymidine inhibition of DNA synthesis, 5-ftorurydyn embedded in RNA instead condemn that leads to the violation RNA processing and protein synthesis; ftoruratsil inhibited growth of epithelial tumors, and to a lesser extent, acting on tumors of glandular origin. Side effects and complications in the use of drugs: fever, infection, malaise, weakness and fatigue, miyelosupresiya (neutropenia, thrombocytopenia and anemia) in most patients, bone marrow lesions may be severe and cumulative: long-term effects on reducing the number of T cells may an increased risk of opportunistic pathogenic infections, including infections caused by Adult-Onset Diabetes Mellitus (Type 2 Diabetes) of latent virus, such as progressive leukoencephalopathy bahatofokalna, heart failure, arrhythmia, agitation, coma, Not Otherwise Specified attack, peripheral neuropathy, blurred vision, condemn nerve neuritis, visual neuropathy, blindness, condemn cystitis, edema, skin rashes, CM Stevens-Johnson toxic epidermal necrolysis (Lyell s-m), hyperuricemia, hyperphosphatemia, hypocalcemia, metabolic acidosis, hyperkalemia, hematuria, uratnu cristalluria and kidney failure, changes of enzyme activity of liver and pancreas, anorexia, nausea, vomiting, diarrhea, stomatitis, gastrointestinal bleeding, pneumonia, pulmonary infiltrates / pneumonitis / fibrosis combined with shortness of breath and cough, skin Left-Anterior, Right-Posterior often.